Canadian Association of Radiologists Journal
Volume 60, Issue 3 , Pages 121-132, June 2009

Abdominal Manifestations of Systemic Lupus Erythematosus: Spectrum of Imaging Findings

  • John M. Kirby, FRCR

      Affiliations

    • Department of Medical Imaging, McMaster University Medical Center, Hamilton, Ontario, Canada
    • Corresponding Author InformationAddress for correspondence: John M. Kirby, FRCR, Department of Medical Imaging, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada.
  • ,
  • Kartik S. Jhaveri, MD

      Affiliations

    • Department of Medical Imaging, University Health Network, Toronto, Ontario, Canada
  • ,
  • Zeev V. Maizlin, MD

      Affiliations

    • Department of Medical Imaging, McMaster University Medical Center, Hamilton, Ontario, Canada
  • ,
  • Mehran Midia, FRCPC

      Affiliations

    • Department of Medical Imaging, McMaster University Medical Center, Hamilton, Ontario, Canada
  • ,
  • Ehsan Haider, FRCPC

      Affiliations

    • Department of Medical Imaging, McMaster University Medical Center, Hamilton, Ontario, Canada
  • ,
  • Korosh Khalili, FRCPC

      Affiliations

    • Department of Medical Imaging, University Health Network, Toronto, Ontario, Canada

Abstract 

Systemic lupus erythematosus is an immune-mediated syndrome in which the immune response is to non–organ-specific antigens, and virtually every organ in the abdominal cavity may become involved. Only renal involvement forms part of the diagnostic criteria, however, a combination of typically nonspecific findings, including peritoneal surface, enteric, renal, renal tract, pancreatic, adrenal, hepatobiliary, and splenic manifestations, should be looked for in patients with known lupus or other connective tissue disease who are undergoing abdominal imaging and may suggest the diagnosis in patients presenting with an acute abdomen. Our work presents the spectrum of imaging findings of abdominal manifestations of systemic lupus erythematosus.

Abrégé 

Le lupus érythémateux disséminé est une maladie auto-immune présentant une réponse immunitaire non propre à un organe. En effet, tous les organes de la cavité abdominale peuvent être touchés. Si l'atteinte rénale constitue un des critères de diagnostic, une combinaison de résultats habituellement aspécifiques, comme les manifestations péritonéales, entériques, rénales, du tractus rénal, pancréatiques, surrénaliennes, hépatobiliaires et spléniques, doit être recherchée chez les patients souffrant de lupus ou d'une autre maladie du tissu conjonctif qui doivent passer un examen d'imagerie abdominale. Ces signes peuvent également suggérer un diagnostic chez les patients avec un abdomen aigu. Nous présentons le spectre complet des résultats d'imagerie des manifestations abdominales du lupus érythémateux disséminé.

Key Words: Abdominal imaging, Computed tomography, Lupus enteritis, Lupus vasculitis, Systemic lupus erythematosus

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PII: S0846-5371(09)00111-9

doi:10.1016/j.carj.2009.06.001

Canadian Association of Radiologists Journal
Volume 60, Issue 3 , Pages 121-132, June 2009