Canadian Association of Radiologists Journal
Volume 61, Issue 3 , Pages 180-183 , June 2010

Answer to Case of the Month #163: Acute Lymphoblastic Leukaemia

  • Jeffery R. Bird, MD, Bsc

      Affiliations

    • Department of Medical Imaging, University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada
    • ,
  • Jennifer R. Tynan, MD

      Affiliations

    • Academic Department of Medical Imaging, University of Saskatchewan, Royal University Hospital, Saskatoon, Saskatchewan, Canada
    • ,
  • Anne K. Dzus, MD, FRCSC

      Affiliations

    • Department of Orthopedic Surgery, University of Saskatchewan, Royal University Hospital, Saskatoon, Saskatchewan, Canada
    • ,
  • David A. Leswick, MD, FRCP(C)

      Affiliations

    • Academic Department of Medical Imaging, University of Saskatchewan, Royal University Hospital, Saskatoon, Saskatchewan, Canada
    • Corresponding Author InformationAddress for correspondence: David A. Leswick, MD, FRCP(C), Department of Medical Imaging, Royal University Hospital, 103 Hospital Drive, Saskatoon, Saskatchewan S7N 0W8, Canada.

References 

  1. Pui CH, Evans WE. Treatment of acute lymphoblastic leukemia. N Engl J Med. 2006;354:166–178
  2. Pui CH, Robison LL, Look AT. Acute lymphoblastic leukaemia. Lancet. 2008;371:1030–1043
  3. Margolin J, Steuber CP, Poplack DG. Acute lymphoblastic leukemia. In:  Piazzo P,  Poplack DG editor. Principles and Practice of Pediatric Oncology. 5th ed. Philadelphia, PA: Lippencott Williams & Wilkins; 2006;p. 538–590
  4. Jonsson OG, Sartain P, Ducore JM, et al. Bone pain as an initial symptom of childhood acute lymphoblastic leukemia: association with nearly normal hematologic indexes. J Pediatr. 1990;117:233–237
  5. Sinigaglia R, Gigante C, Bisinella G, et al. Musculoskeletal manifestations in pediatric acute leukemia. J Pediatr Orthop. 2008;28:20–28
  6. Bernard EJ, Nicholls WD, Howman-Giles RB, et al. Patterns of abnormality on bone scans in acute childhood leukemia. J Nucl Med. 1998;39:1983–1986
  7. Urs L, Stevens L, Kahwash S. Leukemia presenting as solid tumors: report of four pediatric cases and review of the literature. Pediatr Dev Pathol. 2008;11:370–376
  8. Liu HC, Hung GY, Yen HJ, et al. Acute sciatica: an unusual presentation of extramedullary relapse of acute lymphoblastic leukemia. Int J Hematol. 2007;86:163–165
  9. Chessells JM, Veys P, Kempski H, et al. Long-term follow-up of relapsed childhood acute lymphoblastic leukaemia. Br J Haematol. 2003;123:396–405
  10. Byrd JC, Edenfield WJ, Shields DJ, et al. Extramedullary myeloid cell tumors in acute nonlymphocytic leukemia: a clinical review. J Clin Oncol. 1995;13:1800–1816
  11. Kellenberger CJ, Epelman M, Miller SF, et al. Fast STIR whole-body MR imaging in children. Radiographics. 2004;24:1317–1330
  12. Vande Berg B, Lecouvet FE, Michaux L, et al. Magnetic resonance imaging of the bone marrow in hematological malignancies. Eur Radiol. 1998;8:1335–1344
  13. Moore SG, Gooding CA, Brasch RC, et al. Bone marrow in children with acute lymphocytic leukemia: MR relaxation times. Radiology. 1986;160:237–240
  14. Babyn PS, Ranson M, McCarville ME. Normal bone marrow: signal characteristics and fatty conversion. Magn Reson Imaging Clin N Am. 1998;6:473–495
  15. Ruzal-Shapiro C, Berdon WE, Cohen MD, et al. MR imaging of diffuse bone marrow replacement in pediatric patients with cancer. Radiology. 1991;181:587–589
  16. Bohndorf K, Benz-Bohm G, Gross-Fengels W, et al. MRI of the knee region in leukemic children. Part I. Initial pattern in patients with untreated disease. Pediatr Radiol. 1990;20:179–183

PII: S0846-5371(09)00219-8

doi: 10.1016/j.carj.2009.10.012

Canadian Association of Radiologists Journal
Volume 61, Issue 3 , Pages 180-183 , June 2010

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