Canadian Association of Radiologists Journal
Volume 61, Issue 5 , Pages 258-264 , December 2010

Image Quality in Low-dose Multidetector Computed Tomography: A Pilot Study to Assess Feasibility and Dose Optimization in Whole-body Bone Imaging

  • Tadhg G. Gleeson, FFRRCSI, MRCPI, LRSI, BCh, BAO (NUI)

      Affiliations

    • Department of Radiology and Diagnostic Imaging, Mater Misericordiae University Hospital, Dublin, Ireland
    • Corresponding Author InformationAddress for correspondence: Tadhg G. Gleeson, Department of Radiology and Diagnostic Imaging, Wexford General Hospital, Wexford, Ireland.
    • ,
  • Brenda Byrne, BSc, MSc

      Affiliations

    • Department of Medical Physics, Mater Misericordiae University Hospital, Dublin, Ireland
    • ,
  • Pat Kenny, PhD, BSc, MSc

      Affiliations

    • Department of Medical Physics, Mater Misericordiae University Hospital, Dublin, Ireland
    • ,
  • Jason Last, MD, PhD

      Affiliations

    • Department of Anatomy, University College Dublin, Earlsfort Terrace, Dublin, Ireland
    • ,
  • Patricia Fitzpatrick, MD, MRCPI, PhD

      Affiliations

    • School of Public Health and Population Science, University College Dublin, Earlsfort Terrace, Dublin, Ireland
    • ,
  • Peter O'Gorman, MD, MRCPI

      Affiliations

    • Department of Haematology, Mater Misericordiae University Hospital, Dublin, Ireland
    • ,
  • Steven J. Eustace, MD, FFRRCSI, PhD, MRCPI

      Affiliations

    • Department of Radiology and Diagnostic Imaging, Mater Misericordiae University Hospital, Dublin, Ireland

References 

  1. D'Sa S, Abildgaard N, Tighe J, et al. Guidelines for the use of imaging in the management of myeloma. Br J Haematol. 2007;137:49–63
  2. Angtuaco EJC, Fassas AB, Walker R, et al. Multiple myeloma: clinical review and diagnostic imaging. Radiology. 2004;231:11–23
  3. Durie BG. The role of anatomic and functional staging in myeloma: description of Durie/Salmon plus staging system. Eur J Cancer. 2006;42:1539–1543
  4. Mahnken AH, Wildberger JE, Gehbauer G, et al. Multidetector CT of the spine in multiple myeloma: comparison with MR imaging and radiography. AJR Am J Roentgenol. 2002;178:1429–1436
  5. Amis ES, Butler PF, Applegate KE, et al. American College of Radiology white paper on radiation dose in medicine. J Am Coll Radiol. 2007;4:272–284
  6. Brenner DJ, Hall EJ, Phil D. Computed tomography: an increasing source of radiation exposure. N Engl J Med. 2007;357:2277–2284
  7. Horger M, Claussen CD, Bross-Bach U, et al. Whole-body low-dose multidetector row-CT in the diagnosis of multiple myeloma: an alternative to conventional radiography. Eur J Rad. 2005;54:289–297
  8. Horger M, Kanz L, Denecke B, et al. The benefit of using whole-body, low-dose, nonenhanced, multidetector computed tomography for follow-up and therapy response monitoring in patients with multiple myeloma. Cancer. 2007;109:1617–1626
  9. Begemann PG, Mahnken A, Ries T, et al. 16-Row multidetector CT of the pelvis after iliosacrally inserted osteosynthetic screws: experimental study of dose adjustment on preserved human cadaver specimens. Fortschr Rontgenstr. 2006;178:1022–1027[German]
  10. Gurung J, Khan MF, Maataoui A, et al. Multislice CT of the pelvis: dose reduction with regard to image quality using 16-row CT. Eur Radiol. 2005;15:1898–1905
  11. Gleeson TG, Moriarty J, Shortt CP, et al. Accuracy of whole-body low-dose multidetector CT (WBLDCT) versus skeletal survey in the detection of myelomatous lesions, and correlation of disease distribution with whole-body MRI (WBMRI). Skeletal Radiol. 2009;38:225–236
  12. Chassang M, Grimaud A, Cucchi JM, et al. Can low-dose computed tomographic scan of the spine replace conventional radiography? An evaluation based on imaging myelomas, bone metastases, and fractures from osteoporosis. Clin Imaging. 2007;31:225–227

PII: S0846-5371(10)00021-5

doi: 10.1016/j.carj.2010.01.003

Canadian Association of Radiologists Journal
Volume 61, Issue 5 , Pages 258-264 , December 2010

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