Canadian Association of Radiologists Journal
Volume 62, Issue 3 , Pages 190-196, August 2011

Serous Cystadenomas of the Pancreas: Long-term Follow-up Measurement of Growth Rate

  • Alexandre Menard, MD

      Affiliations

    • Department of Medical Imaging, St Michael's Hospital, Toronto Ontario, Canada
  • ,
  • George Tomlinson, PhD

      Affiliations

    • Division of Clinical Decision-Making and Health Care, Toronto General Hospital, Toronto, Ontario, Canada
  • ,
  • Sean Cleary, MD

      Affiliations

    • Hepatobiliary and Pancreatic Surgical Oncology University Health Network, University of Toronto Division of General Surgery, Toronto General Hospital, Toronto, Ontario, Canada
  • ,
  • Alice Wei, MD

      Affiliations

    • Hepatobiliary and Pancreatic Surgical Oncology University Health Network, University of Toronto Division of General Surgery, Toronto General Hospital, Toronto, Ontario, Canada
  • ,
  • Steven Gallinger, MD

      Affiliations

    • Hepatobiliary and Pancreatic Surgical Oncology University Health Network, University of Toronto Division of General Surgery, Toronto General Hospital, Toronto, Ontario, Canada
  • ,
  • Masoom A. Haider, MD

      Affiliations

    • Joint Department of Medical Imaging, University Health Network and Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
    • Corresponding Author InformationAddress for correspondence: Masoom A. Haider, MD, Department of Medical Imaging University Health Network, Princess Margaret Hospital and Mount Sinai Hospital, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada.

published online 24 May 2010.

Abstract 

Purpose

To measure the growth rate of microcystic subtype serous adenomas of the pancreas diagnosed by imaging.

Methods

For this retrospective study, 241 imaging studies were reviewed from 1998 to 2005. Thirty-one patients met our strict diagnostic imaging inclusion criteria and had at least 18 months of imaging follow-up. Patient demographics and lesion imaging characteristics were tested as predictors of growth.

Results

Growth was measured over a mean period of 42 months. There was a significant (P = .0004) linear growth of tumour for the population. There was significant clustering (P = .001) of the population into 2 growth rates: 0.50 mm/y (n = 23) and 5.5 mm/y (n = 8). The diameter of the lesion at presentation was significantly correlated with growth (r = 0.45; P = .01).

Conclusion

The microcystic subtype of serous cystadenomas of the pancreas diagnosed with imaging criteria demonstrates 2 distinct and slow growth rates. The size of the lesion at presentation is correlated with growth rate.

Résumé 

Objectif

Mesurer la vitesse de croissance de l'adénome séreux du pancréas, de sous-type microkystique, diagnostiqué par imagerie.

But

Pour cette étude rétrospctive, 241 examens d'imagerie effectués de 1998 à 2005 ont été revus. 31 patients rencontraient nos critères diagnostiques rigoureux selon l'imagerie et avaient un suivi d'au moins 18 mois par imagerie. Les données démographiques des patients et les caractéristiques de la lésion à l'imagerie ont été évalués en tant que facteurs prédicteurs de croissance.

Résultas

La croissance a été mesurée sur une période moyenne de 42 mois. On a observé une croissance linéaire significative (P = .0004) de la tumeur. On a noté aussi une nette répartition (P = .001) de la population étudiée en deux groupes , selon la vitesse de croissance : soit un groupe à 0.50mm/an (n = 23) et l'autre à 5.5mm/an (n = 8). Le diamètre de la lésion à la présentation était en nette relation avec la vitesse de croissance.

Conclusion

Le sous-type microkystique du cystadénome séreux du pancréas diagnostiqué selon les critères de l'imagerie démontre deux formes distinctes de vitesse de croissance, chacune étant lente toutefois. La taille de la lésion à la présentation est en rapport avec la vitesse de croissance.

Key Words: Serous adenomas, Growth rate, Pancreas

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S0846-5371(10)00106-3

doi:10.1016/j.carj.2010.04.004

Canadian Association of Radiologists Journal
Volume 62, Issue 3 , Pages 190-196, August 2011