Canadian Association of Radiologists Journal
Volume 62, Issue 4 , Pages 251-255 , November 2011

Diffraction Enhanced X-ray Imaging of the Distal Radius: A Novel Approach for Visualization of Trabecular Bone Architecture

  • David M.L. Cooper, PhD

      Affiliations

    • Department of Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    • Corresponding Author InformationAddress for correspondence: David M. L. Cooper, PhD, Department of Anatomy and Cell Biology, University of Saskatchewan, 107 Wiggins Road, Saskatoon, Saskatchewan S7N 5E5, Canada.
    • ,
  • Brian Bewer, MSc

      Affiliations

    • Department of Physics and Engineering Physics, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    • ,
  • Sheldon Wiebe, MD

      Affiliations

    • Department of Medical Imaging, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    • ,
  • Tomasz W. Wysokinski, PhD

      Affiliations

    • Canadian Light Source, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    • ,
  • Dean Chapman, PhD

      Affiliations

    • Department of Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    • Canadian Light Source, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

References 

  1. Lorrain J, Paiement G, Chevrier N, et al. Population demographics and socioeconomic impact of osteoporotic fractures in Canada. Menopause. 2003;10:228–234
  2. NIH Consensus Development Panel on Osteoporosis Prevention D, and, Therapy. Osteoporosis prevention, diagnosis, and therapy. JAMA. 2001;285:785–795
  3. Bouxsein ML. Technology insight: noninvasive assessment of bone strength in osteoporosis. Nat Clin Pract Rheumatol. 2008;4:310–318
  4. Boutroy S, Bouxsein ML, Munoz F, et al. In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. J Clin Endocrinol Metab. 2005;90:6508–6515
  5. Lespessailles E, Gadois C, Kousignian I, et al. Clinical interest of bone texture analysis in osteoporosis: a case control multicenter study. Osteoporos Int. 2008;19:1019–1028
  6. Chapman D, Thomlinson W, Johnston RE, et al. Diffraction enhanced x-ray imaging. Phys Med Biol. 1997;42:2015–2025
  7. Wysokinski TW, Chapman D, Adams G, et al. Beamlines of the biomedical imaging and therapy facility at the Canadian light source: part 1. Nucl Instrum Methods Phys Res A. 2007;582:73–76
  8. Kiss MZ, Sayers DE, Zhong Z. Measurement of image contrast using diffraction enhanced imaging. Phys Med Biol. 2003;48:325–340
  9. Kelly ME, Beavis RC, Fourney DR, et al. Diffraction-enhanced imaging of the rat spine. Can Assoc Radiol J. 2006;57:204–210
  10. Connor DM, Sayers D, Sumner DR, et al. Diffraction enhanced imaging of controlled defects within bone, including bone-metal gaps. Phys Med Biol. 2006;51:3283–3300
  11. Muehleman C, Li J, Connor D, et al. Diffraction-enhanced imaging of musculoskeletal tissues using a conventional x-ray tube. Acad Radiol. 2009;16:918–923
  12. Cooper DM, Thomas CD, Clement JG, et al. Three-dimensional microcomputed tomography imaging of basic multicellular unit-related resorption spaces in human cortical bone. Anat Rec A Discov Mol Cell Evol Biol. 2006;288:806–816
  13. Faulconer L, Parham C, Connor DM, et al. Radiologist evaluation of an X-ray tube-based diffraction-enhanced imaging prototype using full-thickness breast specimens. Acad Radiol. 2009;16:1329–1337
  14. Nesch I, Fogarty DP, Tzvetkov T, et al. The design and application of an in-laboratory diffraction-enhanced x-ray imaging instrument. Rev Sci Instrum. 2009;80;093702
  15. Parham C, Zhong Z, Connor DM, et al. Design and implementation of a compact low-dose diffraction enhanced medical imaging system. Acad Radiol. 2009;16:911–917

PII: S0846-5371(10)00117-8

doi: 10.1016/j.carj.2010.04.015

Canadian Association of Radiologists Journal
Volume 62, Issue 4 , Pages 251-255 , November 2011

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